| Product Name | ABCA4 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ABCA4 |
| Synonyms | ABC 10 antibody; ABC A4 antibody; ABC transporter; retinal-specific antibody; ABC10 antibody; ABCA 4 antibody; abcA4 antibody; ABCA4_HUMAN antibody; ABCR antibody; ARMD 2 antibody; ARMD2 antibody; ATP binding cassette 10 antibody; ATP binding cassette sub family A member 4 antibody; ATP binding cassette sub family A member4 antibody; ATP binding cassette transporter antibody; ATP binding cassette transporter retinal specific antibody; ATP binding cassette; sub family A (ABC1); member 4 antibody; ATP binding cassette; sub family A (ABC1); member4 antibody; ATP binding cassette10 antibody; ATP binding transporter; retina specific antibody; ATP-binding cassette sub-family A member 4 antibody; CORD 3 antibody; CORD3 antibody; DKFZp781N1972 antibody; FFM antibody; FLJ17534 antibody; Photoreceptor rim protein antibody; Retina specific ABC transporter antibody; Retinal specific ATP binding cassette transporter antibody; Retinal-specific ATP-binding cassette transporter antibody; RIM ABC transporter antibody; RIM protein antibody; RmP antibody; RP 19 antibody; RP19 antibody; Stargardt disease protein antibody; STGD antibody; STGD1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human ABCA4 |
| Isotype | IgG |
| Target | ABCA4 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | P78363 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. |
| Supplier | Cusabio |
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