Product Name | Acetyl-Histone H2B type 1-B(K20)Antibody |
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Description | A synthesized peptide |
Synonyms | Histone H2B type 1-B, Histone H2B.1, Histone H2B.f, H2B/f, HIST1H2BB, H2BFF |
Clonality | Monoclonal |
Clone | 21F11 |
Conjugate | Unconjugated |
Immunogen | A synthesized peptide |
Isotype | Rabbit IgG |
Target | HIST1H2BB |
Reactivity | Human, Mouse |
Applications | ELISA, FC, ICC, IF, WB |
Working Dilutions | Recommended dilution: WB:1:5000-1:10000, ICC:1:50-1:500, IF:1:30-1:200 |
Form | Liquid |
Diluent Buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Uniprot | P33778 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Supplier | Cusabio |
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