| Product Name | Alkyne Phosphoramidite, 5'-terminal |
|---|---|
| Description | Phosphoramidite for the synthesis of oligonucleotides with 5'-terminal alkyne for Click Chemistry. This alkyne amidite has several advantages over 5'-hexynyl phosphoramidite, 5'-butynyl-CEP, and other 5'-terminal alkyne phosphoramidites. First, it is solid compound which is easier to handle and dispense. And due to its structure, it is also more stable in solution, and has a longer shelf life. The diluent for this phosphoramidite is acetonitrile. 5 min coupling time is recommended. Because this amidite does not contain 5'-terminal DMT group, no 5'-deprotection is needed. Oligonucleotides should be deblocked under standard conditions, and purified by PAGE, or ion exchange HPLC. Oligonucleotides with this modification are ideal for use in Click Chemistry. |
| Molecular Weight | 409.50 kDa |
| Form | Colorless solid. |
| Purity | 95% (by 1H and 31P NMR, and HPLC-MS). |
| Cas Number | 1417539-32-2 |
| Storage | Shipped at room temperature. Upon delivery, store at -20°C. Desiccate. |
| Supplier | Antibodies.com |
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