Product Name | AMIGO2 Antibody |
---|---|
Description | Rabbit polyclonal antibody to AMIGO2 |
Synonyms | Adhesion molecule with Ig like domain 2 antibody; ALI 1 antibody; ALI1 antibody; Alivin 1 antibody; Alivin-1 antibody; Alivin1 antibody; AMGO2_HUMAN antibody; AMIGO 2 antibody; AMIGO-2 antibody; Amigo2 antibody; Amphoterin induced gene 2 antibody; Amphoterin induced protein 2 antibody; Amphoterin-induced gene and open reading frame 2 antibody; Amphoterin-induced protein 2 antibody; DEGA antibody; Differentially expressed in gastric adenocarcinoma antibody; Differentially expressed in gastric adenocarcinomas antibody; Transmembrane protein AMIGO 2 antibody; Transmembrane protein AMIGO2 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Fusion protein of human AMIGO2 |
Isotype | IgG |
Target | AMIGO2 |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IHC, WB |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q86SJ2 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction |
Supplier | Cusabio |
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