Anti-A Blood Group antigen Monoclonal Antibody, Culture Supernatant
| Product Name | Anti-A Blood Group antigen Monoclonal Antibody, Culture Supernatant |
|---|---|
| Description | Mouse monoclonal antibody to human Blood Group A Antigen Culture supernatant. The histo-blood group A antigen is defined by the carbohydrate structure at the non-reducing termini of oligosaccharide chains of glycoproteins and glycolipids. Carbohydrate chains are synthesized by the action of alpha -Nacetyl-D-galactosaminyl-transferase, which catalyzes the transfer of GalNAc monosaccharide to an acceptor substrate, the H antigen. The structure of the A antigen is : GalNAc (alpha 1-3)Gal(beta 1-3)GlcNAc-R-Fuc (alpha 1-2). The A antigen is divided into 2 main subgroups, A1 and A. |
| Synonyms | Bllod group A antigen |
| Clonality | Monoclonal |
| Clone | BRIC 145 |
| Immunogen | Blood Group A antigen was made in response to immunisation with A active ovarian cyst glycoprotein. |
| Isotype | Mouse IgG1 kappa light chain |
| Reactivity | Human |
| Applications | FC, ICC, IP, WB |
| Form | Culture Supernatant |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | 1. Curtis B.R et al. (2000) Blood group A and B antigens are strongly expressed on platelets of some individuals. Blood 96: 1574-1581. 2. Achermann F.J. et al. (2005) Soluble type A substance in fresh-frozen plasma as a function of ABO and Secretor genotypes and Lewis phenotype. Transfusion and Apheresis Science 32 255-262. 3. Anstee DJ, Cartron J-P. (1997) Towards an understanding of the red cell surface. In:Garratty G, ed. Applications of molecular biology to transfusion medicine:17-49. American Association of Blood Banks, Bethesda, MD. 4. Daniels G. (2002) Human blood groups (second Ed.). Blackwell Science Ltd , Oxford , UK . 5. Issitt PD, Anstee DJ (1998) Applied blood group serology. 4th edn. Montgomery Scientific Publications, Durham, NC. 6. Mollison PL, Engelfriet CP, Contreras M. (1997) Blood Transfusion in clinical medicine. 10th edn. Blackwell Science, Oxford. 7. Reid ME, Lomas-Francis C. (1997) The blood group antigen facts book. Academic Press, London. |
| Supplier | ARP |
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