| Product Name | Anti-CD48 (Pan Leukocyte Marker), Monoclonal Antibody |
|---|---|
| Description | Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. |
| Synonyms | B cell membrane protein, B-cell activation marker, BCM1 surface antigen, BLAST1, Signaling lymphocytic activation molecule 2, SLAM family member 2 (SLAMF2), TCT.1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5-4.8 |
| Immunogen | Human peripheral blood lymphocytes |
| Isotype | IgG2a, kappa |
| Reactivity | Human |
| Applications | FC, IF |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 962 |
| Uniprot | P09326 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Vaughan HA et al. The isolation of cDNA clones for CD48. Immunogenetics 1991, 33(2):113-117.Vaughan HA et al. Hu Ly-M3--a human leukocyte antigen. Transplantation 1983, 36(4):446-450 |
| Supplier | ARP |
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