| Product Name | Anti-Interferon gamma (IFNG), Monoclonal Antibody |
|---|---|
| Description | Recognizes a protein of 20-25kDa, identified as human interferon. This monoclonal antibody is specific to human IFN- and recognizes both recombinant and native human IFN-γ. It does not neutralize the activity of IFN-. T lymphocytes and NK cells mainly produce IFN-. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN- (type I interferon). |
| Synonyms | AMCF1, Beta thromboglobulin like protein, CXC chemokine ligand 8 (CXCL8), Emoctakin, Granulocyte chemotactic protein 1 (GCP1), IFG, IFI, IFN Immune, IFN-gamma (IFNG), Interleukin 8, Interferon gamma, LECT, LUCT, Lymphocyte derived neutrophil activating factor, LYNAP, Macrophage Activating Factor (MAF), Monocyte derived neutrophil activating protein (MONAP), Monocyte derived neutrophil chemotactic factor (MDNCF), Neutrophil activating factor (NAF), Neutrophil activating peptide 1 (NAP1), Neutrophil activating protein 1 (NAP1), SCYB8, T cell chemotactic factor, T Cell Interferon, Type II Interferon |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | G-23 |
| Immunogen | Purified recombinant human IFN-gamma |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | FC, IF |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 3458 |
| Uniprot | P01579 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Vilcek J. Forty years of interferon, forty years of cytokines. Cytokine Growth Factor Rev 1997,8(4):239 Farrar MA and Schreiber RD. The molecular cell biology of interferon-gamma and its receptor. Annu Rev Immunol 1993, 11:571-611Vilcek J et al. Induction of human interferon gamma with phorbol esters and phytohemagglutinin. Methods Enzymol 1986,119:48-5 |
| Supplier | ARP |
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