| Product Name | Anti-Mouse CD11b In Vivo Antibody - Low Endotoxin (M1/70) |
|---|---|
| Synonyms | Integrin alpha-M, Itgam, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1 |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | M1/70 |
| Immunogen | B10 mouse spleen cells enriched for T cells |
| Isotype | Rat IgG2b |
| Target | CD11b |
| Specificity | Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) recognizes the (Mr 170 kD) alpha m subunit of Mac-1 (CD11b/CD18, alpha m beta 2 integrin), the mouse macrophage-granulocyte specific antigen. Mac-1 is a macrophage differentiation antigen associated with type three complement receptor and mediates adhesion to CD54 (ICAM-1). |
| Reactivity | Mouse |
| Applications | IHC-Fr, FA, FC, ICC, IP, MC, WB |
| Diluent Buffer | 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Reconstitution | Functional Assay: Activation of mouse peritoneal macrophages Each investigator should determine their own optimal working dilution for specific applications. |
| Concentration | 0.5 mg/ml |
| Purity | >95% by SDS-PAGE and HPLC |
| Uniprot | P05555 |
| Storage | anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
| Notes | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Supplier | Ichorbio |
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