Product Name | BLNK Antibody |
---|---|
Description | Rabbit polyclonal antibody to BLNK |
Synonyms | AGM4 antibody; B cell adapter containing SH2 domain protein antibody; B cell adapter containing Src homology 2 domain protein antibody; B cell adaptor containing SH2 domain antibody; B cell linker antibody; B cell linker protein antibody; B cell-specific adaptor protein antibody; B-cell activation antibody; B-cell adapter containing a SH2 domain protein antibody; B-cell adapter containing a Src homology 2 domain protein antibody; B-cell linker protein antibody; BASH antibody; Bca antibody; BLNK antibody; BLNK s antibody; BLNK_HUMAN antibody; Cytoplasmic adapter protein antibody; Ly 57 antibody; Ly57 antibody; Lymphocyte antigen 57 antibody; Lyw 57 antibody; Lyw57 antibody; MGC111051 antibody; SH2 domain-containing leukocyte protein; 65-KD antibody; SLP 65 antibody; SLP-65 antibody; SLP65 antibody; Src homology [SH2] domain-containing leukocyte protein of 65 kD antibody; Src homology 2 domain containing leukocyte protein of 65 kDa antibody; Src homology 2 domain-containing leukocyte protein of 65 kDa antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthetic peptide of human BLNK |
Isotype | IgG |
Target | BLNK |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IHC |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q8WV28 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. |
Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.