Product Name | BRAP Antibody |
---|---|
Description | Rabbit polyclonal antibody to BRAP |
Synonyms | BRAP antibody; RNF52BRCA1-associated protein antibody; EC 2.3.2.27 antibody; BRAP2 antibody; Impedes mitogenic signal propagation antibody; IMP antibody; RING finger protein 52 antibody; RING-type E3 ubiquitin transferase BRAP2 antibody; Renal carcinoma antigen NY-REN-63 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Recombinant Human BRCA1-associated protein (13-124AA) |
Isotype | IgG |
Target | BRAP |
Reactivity | Human, Rat |
Applications | ELISA, IF, IHC, WB |
Form | Liquid |
Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Uniprot | Q7Z569 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. |
Supplier | Cusabio |
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