| Product Name | CX3CL1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to CX3CL1 |
| Synonyms | A 152E5.2 antibody; AB030188 antibody; ABCD 3 antibody; ABCD3 antibody; AI848747 antibody; C-X3-C motif chemokine 1 antibody; C3Xkine antibody; Chemokine (C-X3-C motif) ligand 1 antibody; Chemokine C X3 C motif ligand 1 antibody; Chemokine CX3C Motif Ligand 1 antibody; CX3C membrane anchored chemokine antibody; CX3C membrane-anchored chemokine antibody; Cx3cl1 antibody; CXC 3 antibody; CXC3 antibody; CXC3C antibody; D8Bwg0439e antibody; FKN antibody; Fractalkine antibody; Neurotactin antibody; NTN antibody; NTT antibody; Processed fractalkine antibody; SCYD 1 antibody; SCYD1 antibody; Small inducible cytokine D1 antibody; Small inducible cytokine subfamily D (Cys X3 Cys) member 1 antibody; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) antibody; Small inducible cytokine subfamily D member 1 antibody; Small-inducible cytokine D1 antibody; X3CL1_HUMAN antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human CX3CL1 |
| Isotype | IgG |
| Target | CX3CL1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | P78423 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene encodes a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine (in humans) and neurotactin (in mice).The polypeptide structure of CXC3L1 differs from the typical structure of other chemokines.CX3CL1 is produced as a long protein (with 373-amino acid in humans) with an extended mucin-like stalk and a chemokine domain on top. The mucin-like stalk permits it to bind to the surface of certain cells. However a soluble (90 kD) version of this chemokine has also been observed. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound chemokine promotes strong adhesion of leukocytes to activated endothelial cells, where it is primarily expressed. CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1. Its gene is located on human chromosome 16 along with some CC chemokines known as CCL17 and CCL22. |
| Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
