| Product Name | GRK6 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to GRK6 |
| Synonyms | FLJ32135 antibody; G protein coupled receptor kinase 6 antibody; G protein coupled receptor kinase GRK6 antibody; G protein-coupled receptor kinase 6 antibody; G protein-coupled receptor kinase GRK6 antibody; Gprk6 antibody; Grk6 antibody; GRK6_HUMAN antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human G protein-coupled receptor kinase 6 protein (1-170AA) |
| Isotype | IgG |
| Target | GRK6 |
| Reactivity | Human, Rat |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | P43250 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
| Supplier | Cusabio |
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