HDAC9 Antibody

Category: Antibodies
Catalog
CSB-PA831141
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Product Name HDAC9 Antibody
Description Rabbit polyclonal antibody to HDAC9
Synonyms HD 7 antibody; HD 7B antibody; HD 9 antibody; HD7 antibody; HD7B antibody; HD9 antibody; HDAC 7 antibody; HDAC 7B antibody; HDAC 9 antibody; HDAC 9B antibody; HDAC 9FL antibody; HDAC antibody; HDAC7 antibody; HDAC7B antibody; HDAC9 antibody; HDAC9_HUMAN antibody; HDAC9B antibody; HDAC9FL antibody; HDRP antibody; Histone deacetylase 4/5 related protein antibody; Histone deacetylase 7 antibody; Histone deacetylase 7B antibody; Histone deacetylase 9 antibody; Histone deacetylase 9A antibody; Histone deacetylase related protein antibody; Histone deacetylase-related protein antibody; KIAA0744 antibody; MEF2 interacting transcription repressor MITR antibody; MEF2 interacting transcription repressor protein antibody; MEF2-interacting transcription repressor MITR antibody; MITR antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthesized peptide derived from human HDAC9.
Isotype IgG
Target HDAC9
Reactivity Human
Applications ELISA, IF, IHC, WB
Form liquid
Diluent Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Uniprot Q9UKV0
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.

Michael Haberland, Mol. Cell. Biol., Jan 2007; 27: 518 - 525.
Xianbo Zhou, PNAS, Sep 2001; 98: 10572.
Kevin Petrie, J. Biol. Chem., Apr 2003; 278: 16059 - 16072.
Kevin Petrie, Blood (ASH Annual Meeting Abstracts), Nov 2004; 104: 1120.

Supplier Cusabio

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