Product Name | HORMAD1 Antibody, HRP conjugated |
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Description | Rabbit polyclonal antibody against HORMAD1 conjugated to HRP. |
Synonyms | HORMAD1 antibody; NOHMA antibody; HORMA domain-containing protein 1 antibody; Cancer/testis antigen 46 antibody; CT46 antibody; Newborn ovary HORMA protein antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | HRP |
Immunogen | Recombinant human HORMA domain-containing protein 1 protein (201-394AA) |
Isotype | IgG |
Target | HORMAD1 |
Reactivity | Human |
Applications | ELISA |
Form | Liquid |
Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Uniprot | Q86X24 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. |
Supplier | Cusabio |
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