| Product Name | HSD17B1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to HSD17B1 |
| Synonyms | 17 beta HSD 1 antibody; 17 beta hydroxysteroid dehydrogenase type 1 antibody; 17-beta-HSD 1 antibody; 17-beta-hydroxysteroid dehydrogenase type 1 antibody; 20 alpha-hydroxysteroid dehydrogenase antibody; 20-alpha-HSD antibody; DHB1_HUMAN antibody; E17KSR antibody; E2DH antibody; EDH17B1 antibody; EDH17B2 antibody; EDHB17 antibody; Estradiol 17 beta dehydrogenase 1 antibody; Estradiol 17-beta-dehydrogenase 1 antibody; HSD17 antibody; HSD17B1 antibody; Hydroxysteroid (17 beta) dehydrogenase 1 antibody; MGC13814 antibody; Placental 17 beta hydroxysteroid dehydrogenase antibody; Placental 17-beta-hydroxysteroid dehydrogenase antibody; SDR28C1 antibody; Short chain dehydrogenase/reductase family 28CE,member 1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human HSD17B1 |
| Isotype | IgG |
| Target | HSD17B1 |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | P14061 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy. |
| Supplier | Cusabio |
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