| Product Name | IFT57 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to IFT57 |
| Synonyms | CDNA FLJ10147 fis clone HEMBA1003369 antibody; Dermal papilla derived protein 8 antibody; Dermal papilla-derived protein 8 antibody; DERP 8 antibody; DERP8 antibody; Esrrbl 1 antibody; Esrrbl1 antibody; ESRRBL1 protein antibody; Estrogen related receptor beta like 1 antibody; Estrogen related receptor beta like protein 1 antibody; Estrogen-related receptor beta-like protein 1 antibody; FLJ10147 antibody; Hip1 Interacting protein antibody; HIP1 interacting protein HIPPI antibody; Hip1 protein interactor antibody; HIP1-interacting protein antibody; HIPPI antibody; Huntingtin interacting protein 1 interacting protein antibody; Huntingtin interacting protein 1 protein interactor antibody; IFT 57 antibody; ift57 antibody; IFT57_HUMAN antibody; Intraflagellar transport 57 homolog (Chlamydomonas) antibody; Intraflagellar transport 57 homolog antibody; Intraflagellar transport protein 57 homolog antibody; MHS4R2 antibody; Vestrogen related receptor beta like 1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Intraflagellar transport protein 57 homolog protein (170-429AA) |
| Isotype | IgG |
| Target | IFT57 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Uniprot | Q9NWB7 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
| Supplier | Cusabio |
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