| Product Name | IQGAP3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to IQGAP3 |
| Synonyms | IQ motif containing GTPase activating protein 3 antibody; IQGA3_HUMAN antibody; IQGAP 3 antibody; IQGAP3 antibody; MGC10170 antibody; MGC10831 antibody; MGC1947 antibody; OTTHUMP00000031854 antibody; OTTHUMP00000031855 antibody; Ras GTPase activating like protein IQGAP3 antibody; Ras GTPase-activating-like protein IQGAP3 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human IQGAP3 |
| Isotype | IgG |
| Target | IQGAP3 |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q86VI3 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, ParkinsonÕs disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Supplier | Cusabio |
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