| Product Name | LL 37 (13-37) (human) |
|---|---|
| Description | LL 37 (13-37) (human), also known as IG 27, is a peptide fragment composed of the C-terminal residues 13-37 of the antimicrobial peptide LL37 [AM-001]. LL37 (13-37) has been show to have antibacterial activity against E. coli, antifungal activity against C. albicans and antiviral activity, blocking the action of HIV-1 reverse transcriptase. LL 37 (13-37) is also active against cancer cells, inhibiting the proliferation of drug-resistant and drug-sensitive carcinoma cells. |
| Synonyms | IG 27 |
| Molecular Weight | 3043.6 Da |
| Target | Antibacterials,Antivirals,Antifungals |
| Amino Acid Sequence | IGKEFKRIVQRIKDFLRNLVPRTES |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store dark, frozen and desiccated |
| Notes | Modifications: None |
| References |
Li et al (2006) Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region. J. Am. Chem. Soc. 128(17) 5776 PMID: 16637646 Wu et al (2010) Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications. Int. J. Cancer. 127(8) 1741 PMID: 20521250Wong et al (2011) Antifungal action of human cathelicidin fragment (LL13-37) on Candida albicans. Peptides 32(10) 1996 PMID: 21889964 Related areas All antimicrobial peptides >All antifungal agents >All antiviral agents >All immunology research categories >All cancer research categories > |
| Supplier | Isca Biochemicals Limited |
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