Product Name | MARK1 Antibody |
---|---|
Description | Rabbit polyclonal antibody to MARK1 |
Synonyms | KIAA1477 antibody; MAP/microtubule affinity regulating kinase 1 antibody; MAP/microtubule affinity-regulating kinase 1 antibody; MARK 1 antibody; MARK antibody; Mark1 antibody; MARK1_HUMAN antibody; MGC126512 antibody; MGC126513 antibody; Serine/threonine protein kinase MARK1 antibody; Serine/threonine-protein kinase MARK1 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Fusion protein of human MARK1 |
Isotype | IgG |
Target | MARK1 |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, WB |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q9P0L2 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart. |
Supplier | Cusabio |
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