| Product Name | MGEA5 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to MGEA5 |
| Synonyms | Beta-hexosaminidase antibody; Beta-N-acetylglucosaminidase antibody; Beta-N-acetylhexosaminidase antibody; Bifunctional protein NCOAT antibody; HEXC antibody; Hyaluronidase in meningioma antibody; KIAA0679 antibody; MEA5 antibody; Meningioma expressed antigen 5 antibody; Meningioma-expressed antigen 5 antibody; MGEA 5 antibody; Mgea5 antibody; N-acetyl-beta-D-glucosaminidase antibody; N-acetyl-beta-glucosaminidase antibody; NCOAT antibody; Nuclear cytoplasmic O GlcNAcase and acetyltransferase antibody; Nuclear cytoplasmic O-GlcNAcase and acetyltransferase antibody; OGA antibody; OGA_HUMAN antibody; Protein O-GlcNAcase antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human MGEA5 |
| Isotype | IgG |
| Target | MGEA5 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | O60502 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas. |
| Supplier | Cusabio |
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