| Product Name | Mouse 5-Nucleotidase (5-NT) ELISA Kit |
|---|---|
| Description | 5'-nucleotidase (EC 3.1.3.5) is an enzyme which catalyzes the phosphorylytic cleavage of 5'nucleotides. Although originally found in snake venom, the activity of 5'nucleotidase has been described for bacteria and plant cells, and is widely distributed in vertebrate tissue. In mammalian cells the enzyme is predominantly located in the plasma membrane and its primary role is in the conversion of extracellular nucleotides (e.g. 5'-AMP), which are generally impermeable, to the corresponding nucleoside (e.g. adenosine) which can readily enter most cells. Consequently, the enzyme plays a key role in the metabolism of nucleotides. This assay has high sensitivity and excellent specificity for detection of Mouse 5-NT. No significant cross-reactivity or interference between Mouse 5-NT and analogues was observed. |
| Method | Sandwich ELISA |
| Detection Range | 0.125-8 mU/mL |
| Sensitivity | 0.031 mU/mL |
| Reactivity | Mouse |
| Sample Types | Serum, Plasma, Other biological fluids. |
| Background | 5'-nucleotidase (EC 3.1.3.5) is an enzyme which catalyzes the phosphorylytic cleavage of 5'nucleotides. Although originally found in snake venom, the activity of 5'nucleotidase has been described for bacteria and plant cells, and is widely distributed in vertebrate tissue. In mammalian cells the enzyme is predominantly located in the plasma membrane and its primary role is in the conversion of extracellular nucleotides (e.g. 5'-AMP), which are generally impermeable, to the corresponding nucleoside (e.g. adenosine) which can readily enter most cells. Consequently, the enzyme plays a key role in the metabolism of nucleotides. |
| Supplier | Abebio |
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