Mouse anti-CD56, Neural Cell Adhesion Molecule, NCAM, clone 123C3 (Monoclonal), sample
| Product Name | Mouse anti-CD56, Neural Cell Adhesion Molecule, NCAM, clone 123C3 (Monoclonal), sample |
|---|---|
| Description | Mouse anti-CD56, Neural Cell Adhesion Molecule, NCAM, clone 123C3 (Monoclonal) |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 123C3 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1 |
| Reactivity | Human |
| Applications | IHC-Fr, IF, IHC-P |
| Working Dilutions | ,IHC-fr (1:50), |
| Diluent Buffer | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration | 100 ug/ml |
| Storage | 2-8°C |
| Notes | The antibody recognizes a transmembrane glycoprotein of 140 and 180 kD which has been identified as NCAM (Neural Cell Adhesion Module). At the international Workshop on SCLC antibodies 123C3 has been categorized as cluster 1 antibody. All cells in small cell carcinomas and carcinoids of the lung are strongly positive for 123C3. A minority of cases of other major types of lung carcinoma are sometimes positive as well: however this positivity is generally weak and focal. Adenoid cystic carcinomas of bronchial glands are strongly positive. Neuroblastoma's and Wilms tumors are usually also staining strongly positive. In non-small lung cell carcinomas, 123C3 staining has been associated with more advanced stage and a decreased survival after surgery. |
| References | Moolenaar et al. Cancer Res 1990;50:1102. Kibbelaar et al. Eur J Cancer 1991;27:431. Stahel et al. Int J Cancer suppl 1994;8:6. Tsang et al. Am J Surg Pathol 1996;20:202 |
| Supplier | MONOSAN |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
