| Product Name | Mouse Protein MTO1 homolog, mitochondrial (MTO1) ELISA Kit |
|---|---|
| Description | Mouse Protein MTO1 homolog, mitochondrial (MTO1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MTO1. No significant cross-reactivity or interference between Mouse MTO1 and analogues was observed. MTO1 encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The mitochondrial tRNA translation optimization 1 may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. This Mouse Protein MTO1 homolog, mitochondrial (MTO1) ELISA Kit employs a two-site sandwich ELISA to quantitate MTO1 in samples. An antibody specific for MTO1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMTO1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MTO1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MTO1 bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Synonyms | MTO1, CGI-02, homolog of yeast Mto1, mitochondrial MTO1-3, mitochondrial translation optimization 1 homolog |
| Method | Sandwich ELISA |
| Detection Range | Please inquire |
| Sensitivity | Please inquire |
| Reactivity | Mouse |
| Sample Types | Cell culture supernatants, Serum, Plasma, Other biological fluids |
| Gene Id | 25821 |
| Storage | 2-8°C |
| Background | MTO1 encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The mitochondrial tRNA translation optimization 1 may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Supplier | Abbkine |
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