| Product Name | Mouse/Rabbit anti-Mammaglobin Cocktail, clone 304-1A5/31A5 |
|---|---|
| Description | Mouse/Rabbit anti-Mammaglobin Cocktail, clone 304-1A5/31A5 |
| Host | Rabbit and Mouse |
| Clonality | Monoclonal |
| Clone | 304-1A5/31A5 |
| Immunogen | Unknown or proprietery to MONOSAN and/or its suppliers |
| Isotype | IgG1, IgG |
| Reactivity | Human |
| Applications | IHC-P |
| Diluent Buffer | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Concentration | n/a |
| Storage | 2-8°C |
| Notes | Mammaglobin is breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Anti-mammaglobin labels cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Absence of mammaglobin expression is typically seen in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung and thyroid tissue.2,5 Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin. |
| References | Fleming TP et al. Ann NY Acad Sci 2000;923:78-89. Bhargava R, et al. Am J Clin Pathol. 2007; 127:103-13. Wang Z, et al. Int J Clin Exp Pathol. 2009; 2:384-9. Han JH, et al. Arch Pathol Lab Med. 2003; 127:1330-4. Zafrakas M, et al. BMC Cancer. 2006; 6:88 |
| Supplier | MONOSAN |
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