| Product Name | (NaeNspeNspe)2-NH2 |
|---|---|
| Description | Peptoids are peptide-mimicking poly-N-substituted glycines, which exhibit enhanced physiological stability and are known to have qualities. They have recently been shown to have activity against Leishmania mexicana axenic amastigotes. Nae is the N-substituted amino ethyl peptoid monomer and Nspe is the (S)-(N-1-phenylethyl)glycine peptoid monomer |
| Synonyms | (NaeNspeNspe)2-NH2, (S)-(N-1-phenylethyl)glycine, N-substituted amino ethyl, Nae, Nae-Nspe-Nspe-Nae-Nspe-Nspe-NH2, Nspe, Peptoids, antibacterial, antiparasitic, poly-N-substituted glycines |
| Molecular Weight | 862.1 Da |
| Target | Antibacterials |
| Amino Acid Sequence | Nae-Nspe-Nspe-Nae-Nspe-Nspe-NH2 |
| Form | Freeze dried solid |
| Purity | >90% By HPLC |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: For more information about peptoids and their nomenclature please refer to the peptide resources page |
| References |
Chongsiriwatana et al (2008) Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc. Natl. Acad. Sci 105(8) 2794 DOI: 10.1073/pnas.0708254105 Zuckermann (2011) Peptoid origins. Biopolymers, 96 545 doi:10.1002/bip.21573 Sun and Zuckermann (2013) Peptoid Polymers: A Highly Designable Bioinspired Material. ACS Nano 7(6) 4715 https://doi.org/10.1021/nn4015714 Huang et al (2014) Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity. PLoS ONE 9(2) e90397. https://doi.org/10.1371/journal.pone.0090397 Eggimann et al (2015) Investigating the Anti€leishmanial Effects of Linear Peptoids. ChemMedChem. 10 233 doi:10.1002/cmdc.201402416 Related areas All peptoids >All antibacterials > |
| Supplier | Isca Biochemicals Limited |
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