| Product Name | NDNL2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to NDNL2 |
| Synonyms | NSMCE3 antibody; HCA4 antibody; MAGEG1 antibody; NDNL2 antibody; Non-structural maintenance of chromosomes element 3 homolog antibody; Non-SMC element 3 homolog antibody; Hepatocellular carcinoma-associated protein 4 antibody; MAGE-G1 antigen antibody; Melanoma-associated antigen G1 antibody; Necdin-like protein 2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human NDNL2 |
| Isotype | IgG |
| Target | NSMCE3 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q96MG7 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). |
| Supplier | Cusabio |
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