Product Name | SH2B2 Antibody |
---|---|
Description | Rabbit polyclonal antibody to SH2B2 |
Synonyms | SH2B2 antibody; APS antibody; SH2B adapter protein 2 antibody; Adapter protein with pleckstrin homology and Src homology 2 domains antibody; SH2 and PH domain-containing adapter protein APS antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthetic peptide of human SH2B2 |
Isotype | IgG |
Target | SH2B2 |
Reactivity | Human, Rat |
Applications | ELISA, IHC |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | O14492 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. |
Supplier | Cusabio |
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