Product Name | SLC17A1 Antibody |
---|---|
Description | Rabbit polyclonal antibody to SLC17A1 |
Synonyms | Na(+)/PI cotransporter 1 antibody; Na/Pi-4 antibody; NAP 1 antibody; Napi1 antibody; NPT 1 antibody; Npt1 antibody; NPT1_HUMAN antibody; Renal Na(+)-dependent phosphate cotransporter 1 antibody; Renal sodium-dependent phosphate transport protein 1 antibody; Renal sodium-phosphate transport protein 1 antibody; Slc17a1 antibody; Sodium phosphate transporter antibody; Sodium-dependent phosphate transport protein 1 antibody; Sodium/phosphate cotransporter 1 antibody; Sodium/phosphate type I cotransporter antibody; Solute carrier family 17 (organic anion transporter) member 1 antibody; solute carrier family 17 (sodium phosphate), member 1 antibody; Solute carrier family 17 (vesicular glutamate transporter) member 1 antibody; Solute carrier family 17 member 1 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthetic peptide of human SLC17A1 |
Isotype | IgG |
Target | SLC17A1 |
Reactivity | Human |
Applications | ELISA, WB |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q14916 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1 and HNF-3º. Indomethacin and salicylate inhibit NPT1-mediated PAH transport. |
Supplier | Cusabio |
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