| Product Name | SLC7A6 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to SLC7A6 |
| Synonyms | SLC7A6 antibody; KIAA0245 antibody; Y+L amino acid transporter 2 antibody; Cationic amino acid transporter antibody; y+ system antibody; Solute carrier family 7 member 6 antibody; y(+)L-type amino acid transporter 2 antibody; Y+LAT2 antibody; y+LAT-2 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Y+L amino acid transporter 2 protein (473-515AA) |
| Isotype | IgG |
| Target | SLC7A6 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Uniprot | Q92536 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells. |
| Supplier | Cusabio |
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