| Product Name | SPC25 Antibody, FITC conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against SPC25 conjugated to FITC. |
| Synonyms | AD024 antibody; hSpc25 antibody; Kinetochore protein Spc25 antibody; SPBC25 antibody; SPC25 antibody; SPC25_HUMAN antibody; spindle pole body component 25 homolog antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | FITC |
| Immunogen | Recombinant human Kinetochore protein Spc25 protein (1-224AA) |
| Isotype | IgG |
| Target | SPC25 |
| Reactivity | Human |
| Applications | ELISA, Dot Blot |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9HBM1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14699129, PubMed:14738735). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735, PubMed:14699129). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). |
| Supplier | Cusabio |
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