| Product Name | TRPC4AP Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to TRPC4AP |
| Synonyms | antibody; TRPC4AP antibody; Chromosome 20 open reading frame 188 antibody; Protein TAP1 antibody; Protein TRUSS antibody; Short transient receptor potential channel 4 associated protein antibody; Short transient receptor potential channel 4-associated protein antibody; TAP1 protein antibody; TNF receptor ubiquitous scaffolding/signaling protein antibody; TNF-receptor ubiquitous scaffolding/signaling protein antibody; TP4AP_HUMAN antibody; Transient receptor potential cation channel; subfamily C; member 4 associated protein antibody; Trp4 associated protein antibody; Trp4-associated protein antibody; Trpc4 associated protein antibody; Trpc4-associated protein antibody; TRPC4AP antibody; TRRP4AP antibody; TRUSS antibody; Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human TRPC4AP |
| Isotype | IgG |
| Target | TRPC4AP |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q8TEL6 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NF_B p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. |
| Supplier | Cusabio |
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