Product Name | WTAP Antibody |
---|---|
Description | Rabbit polyclonal antibody to WTAP |
Synonyms | DKFZp686F20131 antibody; Female-lethal(2)D homolog antibody; FL2D_HUMAN antibody; hFL(2)D antibody; KIAA0105 antibody; MGC3925 antibody; Mum2 antibody; OTTHUMP00000017522 antibody; OTTHUMP00000017523 antibody; PNAS 132 antibody; PNAS-132 antibody; PNAS132 antibody; Pre mRNA splicing regulator WTAP antibody; Pre-mRNA-splicing regulator WTAP antibody; Putative pre mRNA splicing regulator female lethal 2D homolog antibody; Putative pre mRNA splicing regulator female lethal(2D) antibody; Putative pre-mRNA splicing regulator female lethal(2D) homolog antibody; putative pre-mRNA splicing regulator female-lethal(2D) antibody; Wilms tumor 1 associated protein antibody; Wilms tumor 1 associating protein antibody; Wilms tumor 1-associating protein antibody; Wilms' tumor 1 associating protein antibody; Wilms' tumour 1-associating protein antibody; WT1 associated protein antibody; WT1-associated protein antibody; WT1-associating protein antibody; wtap antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Recombinant Human Pre-mRNA-splicing regulator WTAP protein (1-151AA) |
Isotype | IgG |
Target | WTAP |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IF, IHC, WB |
Form | Liquid |
Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Uniprot | Q15007 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724). |
Supplier | Cusabio |
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